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massarray epityper platform  (Sequenom)

 
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    Sequenom massarray epityper platform
    IC1 and MEST methylation levels in the 183 subjects clinically suspected of having Silver-Russell syndrome (SRS) in this study. Subjects with hypermethylated MEST data represented maternal uniparental disomy of chromosome 7. N-H score, Netchine-Harbison clinical scoring system; IC, imprinting center. *Red lines represent upper and lower limits of the reference ranges by the <t>MassARRAY</t> assay (IC1 methylation level: 35-52%, MEST methylation level: 40-69%).
    Massarray Epityper Platform, supplied by Sequenom, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/massarray epityper platform/product/Sequenom
    Average 90 stars, based on 1 article reviews
    massarray epityper platform - by Bioz Stars, 2026-03
    90/100 stars

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    1) Product Images from "Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome"

    Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome

    Journal: International Journal of Medical Sciences

    doi: 10.7150/ijms.84154

    IC1 and MEST methylation levels in the 183 subjects clinically suspected of having Silver-Russell syndrome (SRS) in this study. Subjects with hypermethylated MEST data represented maternal uniparental disomy of chromosome 7. N-H score, Netchine-Harbison clinical scoring system; IC, imprinting center. *Red lines represent upper and lower limits of the reference ranges by the MassARRAY assay (IC1 methylation level: 35-52%, MEST methylation level: 40-69%).
    Figure Legend Snippet: IC1 and MEST methylation levels in the 183 subjects clinically suspected of having Silver-Russell syndrome (SRS) in this study. Subjects with hypermethylated MEST data represented maternal uniparental disomy of chromosome 7. N-H score, Netchine-Harbison clinical scoring system; IC, imprinting center. *Red lines represent upper and lower limits of the reference ranges by the MassARRAY assay (IC1 methylation level: 35-52%, MEST methylation level: 40-69%).

    Techniques Used: Methylation

    Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS with or without each SRS feature.
    Figure Legend Snippet: Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS with or without each SRS feature.

    Techniques Used: Methylation, Biomarker Discovery, Standard Deviation

    Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS in this study with or without each SRS feature according to the Netchine-Harbison (N-H) clinical scoring system.
    Figure Legend Snippet: Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS in this study with or without each SRS feature according to the Netchine-Harbison (N-H) clinical scoring system.

    Techniques Used: Methylation, Biomarker Discovery, Standard Deviation

    The relationships between IC1 methylation level by the MassARRAY assay and z scores of birth weight, birth height, and birth head circumference (HC) in the Silver-Russell syndrome subjects with IC1 hypomethylation. (A) Birth weight z score (n = 28, r = 0.184, p > 0.05). (B) Birth height z score (n = 22, r = 0.184, p > 0.05). (C) Birth HC z score (n = 19, r = -0.416, p > 0.05). IC, imprinting center.
    Figure Legend Snippet: The relationships between IC1 methylation level by the MassARRAY assay and z scores of birth weight, birth height, and birth head circumference (HC) in the Silver-Russell syndrome subjects with IC1 hypomethylation. (A) Birth weight z score (n = 28, r = 0.184, p > 0.05). (B) Birth height z score (n = 22, r = 0.184, p > 0.05). (C) Birth HC z score (n = 19, r = -0.416, p > 0.05). IC, imprinting center.

    Techniques Used: Methylation

    Gender, z scores of birth weight, height, and head circumference, Netchine-Harbison (N-H) score, and IC1 and MEST methylation levels by the MassARRAY assay for the 31 SRS subjects with IC1 hypomethylation.
    Figure Legend Snippet: Gender, z scores of birth weight, height, and head circumference, Netchine-Harbison (N-H) score, and IC1 and MEST methylation levels by the MassARRAY assay for the 31 SRS subjects with IC1 hypomethylation.

    Techniques Used: Methylation



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    IC1 and MEST methylation levels in the 183 subjects clinically suspected of having Silver-Russell syndrome (SRS) in this study. Subjects with hypermethylated MEST data represented maternal uniparental disomy of chromosome 7. N-H score, Netchine-Harbison clinical scoring system; IC, imprinting center. *Red lines represent upper and lower limits of the reference ranges by the <t>MassARRAY</t> assay (IC1 methylation level: 35-52%, MEST methylation level: 40-69%).
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    epityper massarray platform  (Sequenom)
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    NOS3 gene methylation levels vary according to genomic location in HPAEC and HPVEC cells. A . UCSC Genome Browser View of NOS3 showing chromosomal coordinates (Chr7 - chromosome 7), location of HM450 array probes, CpG sites (black vertical dashes), alternative splice variants including differential exons (blue bar) and introns (arrowed lines), CpG islands (green bar). B . Magnified view of regions of differential methylation of the NOS3 gene between HPAEC and HPVEC. C . Graphical summary of mean NOS3 methylation level (y-axis) in HPAEC (open triangles; n=9) relative to HPVEC (closed squares; n=9) for HM450 probes 1–14 in A. (x-axis) highlights a region of methylation of the major NOS3 promoter (i) and reciprocal hypomethylation of a downstream CpG island (iii) in HPVEC relative to HPAEC cells . Error bars denote 95% confidence interval and asterisks denote level of significance of array data according to adjusted p-value from linear regression analysis. D . DNA Methylation patterns detected by Sequenom <t>EpiTYPER</t> around the two regions corresponding to the HM450 probes. This cross-platform analysis further confirms the methylation of the major NOS3 promoter in HPVEC (i) and the reciprocal hypomethylation of the downstream CpG island (ii) Error bars – 95% confidence interval.
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    Image Search Results


    IC1 and MEST methylation levels in the 183 subjects clinically suspected of having Silver-Russell syndrome (SRS) in this study. Subjects with hypermethylated MEST data represented maternal uniparental disomy of chromosome 7. N-H score, Netchine-Harbison clinical scoring system; IC, imprinting center. *Red lines represent upper and lower limits of the reference ranges by the MassARRAY assay (IC1 methylation level: 35-52%, MEST methylation level: 40-69%).

    Journal: International Journal of Medical Sciences

    Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome

    doi: 10.7150/ijms.84154

    Figure Lengend Snippet: IC1 and MEST methylation levels in the 183 subjects clinically suspected of having Silver-Russell syndrome (SRS) in this study. Subjects with hypermethylated MEST data represented maternal uniparental disomy of chromosome 7. N-H score, Netchine-Harbison clinical scoring system; IC, imprinting center. *Red lines represent upper and lower limits of the reference ranges by the MassARRAY assay (IC1 methylation level: 35-52%, MEST methylation level: 40-69%).

    Article Snippet: All diagnostic examinations were performed by methylation profiling of H19 -associated IC1 and the imprinted PEG1/MEST region using MS-HRM and high-resolution quantitative methylation profiling with a methylation-specific PCR assay using the MassARRAY EpiTYPER platform (Sequenom, San Diego, CA, USA).

    Techniques: Methylation

    Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS with or without each SRS feature.

    Journal: International Journal of Medical Sciences

    Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome

    doi: 10.7150/ijms.84154

    Figure Lengend Snippet: Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS with or without each SRS feature.

    Article Snippet: All diagnostic examinations were performed by methylation profiling of H19 -associated IC1 and the imprinted PEG1/MEST region using MS-HRM and high-resolution quantitative methylation profiling with a methylation-specific PCR assay using the MassARRAY EpiTYPER platform (Sequenom, San Diego, CA, USA).

    Techniques: Methylation, Biomarker Discovery, Standard Deviation

    Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS in this study with or without each SRS feature according to the Netchine-Harbison (N-H) clinical scoring system.

    Journal: International Journal of Medical Sciences

    Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome

    doi: 10.7150/ijms.84154

    Figure Lengend Snippet: Quantitative IC1 methylation level using the MassARRAY assay in the 90 subjects with a clinical diagnosis of SRS in this study with or without each SRS feature according to the Netchine-Harbison (N-H) clinical scoring system.

    Article Snippet: All diagnostic examinations were performed by methylation profiling of H19 -associated IC1 and the imprinted PEG1/MEST region using MS-HRM and high-resolution quantitative methylation profiling with a methylation-specific PCR assay using the MassARRAY EpiTYPER platform (Sequenom, San Diego, CA, USA).

    Techniques: Methylation, Biomarker Discovery, Standard Deviation

    The relationships between IC1 methylation level by the MassARRAY assay and z scores of birth weight, birth height, and birth head circumference (HC) in the Silver-Russell syndrome subjects with IC1 hypomethylation. (A) Birth weight z score (n = 28, r = 0.184, p > 0.05). (B) Birth height z score (n = 22, r = 0.184, p > 0.05). (C) Birth HC z score (n = 19, r = -0.416, p > 0.05). IC, imprinting center.

    Journal: International Journal of Medical Sciences

    Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome

    doi: 10.7150/ijms.84154

    Figure Lengend Snippet: The relationships between IC1 methylation level by the MassARRAY assay and z scores of birth weight, birth height, and birth head circumference (HC) in the Silver-Russell syndrome subjects with IC1 hypomethylation. (A) Birth weight z score (n = 28, r = 0.184, p > 0.05). (B) Birth height z score (n = 22, r = 0.184, p > 0.05). (C) Birth HC z score (n = 19, r = -0.416, p > 0.05). IC, imprinting center.

    Article Snippet: All diagnostic examinations were performed by methylation profiling of H19 -associated IC1 and the imprinted PEG1/MEST region using MS-HRM and high-resolution quantitative methylation profiling with a methylation-specific PCR assay using the MassARRAY EpiTYPER platform (Sequenom, San Diego, CA, USA).

    Techniques: Methylation

    Gender, z scores of birth weight, height, and head circumference, Netchine-Harbison (N-H) score, and IC1 and MEST methylation levels by the MassARRAY assay for the 31 SRS subjects with IC1 hypomethylation.

    Journal: International Journal of Medical Sciences

    Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome

    doi: 10.7150/ijms.84154

    Figure Lengend Snippet: Gender, z scores of birth weight, height, and head circumference, Netchine-Harbison (N-H) score, and IC1 and MEST methylation levels by the MassARRAY assay for the 31 SRS subjects with IC1 hypomethylation.

    Article Snippet: All diagnostic examinations were performed by methylation profiling of H19 -associated IC1 and the imprinted PEG1/MEST region using MS-HRM and high-resolution quantitative methylation profiling with a methylation-specific PCR assay using the MassARRAY EpiTYPER platform (Sequenom, San Diego, CA, USA).

    Techniques: Methylation

    NOS3 gene methylation levels vary according to genomic location in HPAEC and HPVEC cells. A . UCSC Genome Browser View of NOS3 showing chromosomal coordinates (Chr7 - chromosome 7), location of HM450 array probes, CpG sites (black vertical dashes), alternative splice variants including differential exons (blue bar) and introns (arrowed lines), CpG islands (green bar). B . Magnified view of regions of differential methylation of the NOS3 gene between HPAEC and HPVEC. C . Graphical summary of mean NOS3 methylation level (y-axis) in HPAEC (open triangles; n=9) relative to HPVEC (closed squares; n=9) for HM450 probes 1–14 in A. (x-axis) highlights a region of methylation of the major NOS3 promoter (i) and reciprocal hypomethylation of a downstream CpG island (iii) in HPVEC relative to HPAEC cells . Error bars denote 95% confidence interval and asterisks denote level of significance of array data according to adjusted p-value from linear regression analysis. D . DNA Methylation patterns detected by Sequenom EpiTYPER around the two regions corresponding to the HM450 probes. This cross-platform analysis further confirms the methylation of the major NOS3 promoter in HPVEC (i) and the reciprocal hypomethylation of the downstream CpG island (ii) Error bars – 95% confidence interval.

    Journal: BMC Genomics

    Article Title: Variable promoter methylation contributes to differential expression of key genes in human placenta-derived venous and arterial endothelial cells

    doi: 10.1186/1471-2164-14-475

    Figure Lengend Snippet: NOS3 gene methylation levels vary according to genomic location in HPAEC and HPVEC cells. A . UCSC Genome Browser View of NOS3 showing chromosomal coordinates (Chr7 - chromosome 7), location of HM450 array probes, CpG sites (black vertical dashes), alternative splice variants including differential exons (blue bar) and introns (arrowed lines), CpG islands (green bar). B . Magnified view of regions of differential methylation of the NOS3 gene between HPAEC and HPVEC. C . Graphical summary of mean NOS3 methylation level (y-axis) in HPAEC (open triangles; n=9) relative to HPVEC (closed squares; n=9) for HM450 probes 1–14 in A. (x-axis) highlights a region of methylation of the major NOS3 promoter (i) and reciprocal hypomethylation of a downstream CpG island (iii) in HPVEC relative to HPAEC cells . Error bars denote 95% confidence interval and asterisks denote level of significance of array data according to adjusted p-value from linear regression analysis. D . DNA Methylation patterns detected by Sequenom EpiTYPER around the two regions corresponding to the HM450 probes. This cross-platform analysis further confirms the methylation of the major NOS3 promoter in HPVEC (i) and the reciprocal hypomethylation of the downstream CpG island (ii) Error bars – 95% confidence interval.

    Article Snippet: NOS3 locus-specific methylation was performed using the Sequenom EpiTYPER MassARRAY platform (Sequenom, San Diego, USA) as previously described [ , ].

    Techniques: Methylation, DNA Methylation Assay